Enzymy: (EC 1.8.x.x) Reakce na S-skupině donorů

EC 1.8.1.x Akceptorem je NAD⁺ nebo NADP⁺

EC označení

Český název

Oficiální IUPAC název

Katalyzovaná reakce

EC 1.8.1.1

odstraněn

EC 1.8.1.2

siřičitan reduktáza (NADPH)

sulfite reductase (NADPH)

H₂S + 3 NADP⁺ + 3 H₂O = siřičitan + 3 NADPH + 3 H⁺

EC 1.8.1.3

hypotaurin dehydrogenáza

hypotaurine dehydrogenase

hypotaurin + H₂O + NAD⁺ = taurin + NADH + H⁺

EC 1.8.1.4

dihydrolipoyl dehydrogenáza

dihydrolipoyl dehydrogenase

protein N⁶-(dihydrolipoyl)lysin + NAD⁺ = protein N⁶-(lipoyl)lysin + NADH + H⁺

EC 1.8.1.5

2-oxopropyl-CoM reduktáza (karboxylující)

2-oxopropyl-CoM reductase (carboxylating)

2-merkaptoethansulfonát + acetoacetát + NADP⁺ = 2-(2-oxopropylthio)ethansulfonát + CO₂ + NADPH

EC 1.8.1.6

cystin reduktáza

cystine reductase

2 L-cystein + NAD⁺ = L-cystin + NADH + H⁺

EC 1.8.1.7

glutathion-disulfid reduktáza

glutathione-disulfide reductase

2 glutathion + NADP⁺ = glutathion disulfid + NADPH + H⁺

EC 1.8.1.8

protein-disulfid reduktáza

protein-disulfide reductase

protein-dithiol + NAD(P)⁺ = protein-disulfid + NAD(P)H + H⁺

EC 1.8.1.9

thioredoxin-disulfid reduktáza

thioredoxin-disulfide reductase

thioredoxin + NADP⁺ = thioredoxin disulfid + NADPH + H⁺

EC 1.8.1.10

CoA-glutathion reduktáza

CoA-glutathione reductase

CoA + glutathion + NADP⁺ = CoA-glutathion + NADPH + H⁺

EC 1.8.1.11

asparagusát reduktáza

asparagusate reductase

3-merkapto-2-merkaptomethylpropanoát + NAD⁺ = asparagusát + NADH + H⁺

EC 1.8.1.12

trypanothion-disulfid reduktáza

trypanothione-disulfide reductase

trypanothion + NADP⁺ = trypanothion disulfid + NADPH + H⁺

EC 1.8.1.13

bis-γ-glutamylcystin reduktáza

bis-γ-glutamylcystine reductase

2 γ-glutamylcystein + NADP⁺ = bis-γ-glutamylcystin + NADPH + H⁺

EC 1.8.1.14

CoA-disulfid reduktáza

CoA-disulfide reductase

2 CoA + NAD(P)⁺ = CoA-disulfid + NAD(P)H + H⁺

EC 1.8.1.15

mykothion reduktáza

mycothione reductase

2 mykothiol + NAD(P)⁺ = mykothion + NAD(P)H + H⁺

EC 1.8.2.x Akceptorem je cytochrom

EC 1.8.2.1

siřičitan dehydrogenáza

sulfite dehydrogenase

siřičitan + 2 ferricytochrom c + H₂O = sulfát + 2 ferrocytochrom c + 2 H+

EC 1.8.2.2

thiosulfát dehydrogenáza

thiosulfate dehydrogenase

2 thiosulfát + 2 ferricytochrom c = tetrathionát + 2 ferrocytochrom c

EC 1.8.3.x Akceptorem je kyslík

EC 1.8.3.1

siřičitanoxidáza

sulfite oxidase

siřičitan + O₂ + H₂O = sulfát + H₂O₂

EC 1.8.3.2

thiol oxidáza

thiol oxidase

4 R'C(R)SH + O₂ = 2 R'C(R)S-S(R)CR' + 2 H₂O

EC 1.8.3.3

glutathion oxidáza

glutathione oxidase

2 glutathion + O₂ = glutathion disulfid + H₂O₂

EC 1.8.3.4

methanthiol oxidáza

methanethiol oxidase

methanthiol + O₂ + H₂O = formaldehyd + H₂S + H₂O₂

EC 1.8.3.5

prenylcystein oxidáza

prenylcysteine oxidase

S-prenyl-L-cystein + O₂ + H₂O = prenal + L-cystein + H₂O₂

EC 1.8.4.x Akceptorem je disulfid

EC 1.8.4.1

glutathion-homocystin transhydrogenáza

glutathione-homocystine transhydrogenase

2 glutathion + homocystin = glutathion disulfid + 2 homocystein

EC 1.8.4.2

protein-disulfid reduktáza (glutathion)

protein-disulfide reductase (glutathione)

2 glutathion + protein-disulfid = glutathion-disulfid + protein-dithiol

EC 1.8.4.3

glutathion-CoA-glutathion

transhydrogenáza

glutathione-CoA-glutathione transhydrogenase

CoA + glutathion disulfid = CoA-glutathion + glutathion

EC 1.8.4.4

glutathion-cystin transhydrogenáza

glutathione-cystine transhydrogenase

2 glutathion + cystin = glutathion disulfid + 2 cystein

EC 1.8.4.5

překlasifikován na EC 1.8.4.13 a EC 1.8.4.14

EC 1.8.4.6

překlasifikován na EC 1.8.4.11

EC 1.8.4.7

enzym-thiol transhydrogenáza (glutathion-disulfid)

enzyme-thiol transhydrogenase (glutathione-disulfide)

[xanthin dehydrogenáza] + glutathion disulfid = [xanthin oxidáza] + 2 glutathion

EC 1.8.4.8

fosfoadenylyl-sulfát reduktáza (thioredoxin)

phosphoadenylyl-sulfate reductase (thioredoxin)

adenosin 3',5'-bisfosfát + siřičitan + thioredoxin disulfid = 3'-fosfoadenylyl sulfát + thioredoxin

EC 1.8.4.9

adenylyl-sulfát reduktáza (glutathion)

adenylyl-sulfate reductase (glutathione)

AMP + siřičitan + glutathion disulfid = adenylyl sulfát + 2 glutathion

EC 1.8.4.10

adenylyl-sulfát reduktáza (thioredoxin)

adenylyl-sulfate reductase (thioredoxin)

AMP + siřičitan + thioredoxin disulfid = 5'-adenylyl sulfát + thioredoxin

EC 1.8.4.11

peptid-methionin (S)-S-oxid reduktáza

peptide-methionine (S)-S-oxide reductase

(1) peptid-L-methionin + thioredoxin disulfid + H₂O = peptid-L-methionin (S)-S-oxid + thioredoxin

(2) L-methionin + thioredoxin disulfid + H₂O = L-methionin (S)-S-oxid + thioredoxin

EC 1.8.4.12

peptid-methionin (R)-S-oxid reduktáza

peptide-methionine (R)-S-oxide reductase

peptid-L-methionin + thioredoxin disulfid + H₂O = peptid-L-methionin (R)-S-oxid + thioredoxin

EC 1.8.4.13

L-methionin (S)-S-oxid reduktáza

L-methionine (S)-S-oxide reductase

L-methionine + thioredoxin disulfid + H₂O = L-methionin (S)-S-oxid + thioredoxin

EC 1.8.4.14

L-methionin (R)-S-oxid reduktáza

L-methionine (R)-S-oxide reductase

L-methionin + thioredoxin disulfid + H₂O = L-methionin (R)-S-oxid + thioredoxin

EC 1.8.5.x Akceptorem je chinon nebo podobná sloučenina

EC 1.8.5.1

glutathion dehydrogenáza (askorbát)

glutathione dehydrogenase (ascorbate)

2 glutathion + dehydroaskorbát = glutathion disulfid + askorbát

EC 1.8.5.2

thiosulfát dehydrogenáza (chinon)

thiosulfate dehydrogenase (quinone)

2 thiosulfát + 6-decylubichinon = tetrathionát + 6-decylubichinol

EC 1.8.6.x Akceptorem je nitroskupina

EC 1.8.6.1

odstraněn, zahrnut do EC 2.5.1.18

EC 1.8.7.x Akceptorem je Fe – S protein

EC 1.8.7.1

siřičitan reduktáza (ferredoxin)

sulfite reductase (ferredoxin)

H₂S + 6 oxidovaný ferredoxin + 3 H₂O = siřičitan + 6 redukovaný ferredoxin + 6 H⁺

EC 1.8.98.x Jiné, známé, akceptory

EC 1.8.98.1

CoB—CoM heterodisulfid reduktáza

CoB—CoM heterodisulfide reductase

koenzym B + koenzym M + methanofenazin = N-{7-[(2-sulfoethyl)dithio]heptanoyl}-O3-fosfo-L-threonin + dihydromethanofenazin

EC 1.8.98.2

sulfiredoxin

sulfiredoxin

peroxiredoxin-(S-hydroxy-S-oxocystein) + ATP + 2 R-SH = peroxiredoxin-(S-hydroxycystein) + ADP + fosfát + R-S-S-R

EC 1.8.99.x Ostatní akceptory

EC 1.8.99.1

siřičitan reduktáza

sulfite reductase

H₂S + akceptor + 3 H₂O = siřičitan + redukovaný akceptor

EC 1.8.99.2

adenylyl-sulfát reduktáza

adenylyl-sulfate reductase

AMP + siřičitan + akceptor = adenylyl sulfát + redukovaný akceptor

EC 1.8.99.3

hydrogensiřičitan reduktáza

hydrogensulfite reductase

trithionát + akceptor + 2 H₂O + OH^- = 3 hydrogensiřičitan + redukovaný akceptor

EC 1.8.99.4

překlasifikován na EC 1.8.4.8